Key features and details
- Rabbit polyclonal to ROX
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ROX antibody
See all ROX primary antibodies
DescriptionRabbit polyclonal to ROX
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human ROX aa 1-190.
Database link: Q8IUF8
- Raji; Jurkat; A431 or 293T cell lysates, HBL435 xenograft
This product was previously labelled as MINA53
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab155335 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 53 kDa.|
|IHC-P||1/100 - 1/1000. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Suggested antigen retrieval using heat mediated 10mM citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).|
FunctionInvolved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Tissue specificityExpressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC), and colon cancer tissues, and in various cancer cell lines.
Sequence similaritiesBelongs to the MINA53/NO66 family.
Contains 1 JmjC domain.
Cellular localizationNucleus. Nucleus > nucleolus.
- Information by UniProt
- 60S ribosomal protein L27a histidine hydroxylase antibody
- Bifunctional lysine specific demethylase and histidyl hydroxylase MINA antibody
- FLJ14393 antibody
ab155335 has been referenced in 1 publication.
- Huo Q et al. Dysfunction of IKZF1/MYC/MDIG axis contributes to liver cancer progression through regulating H3K9me3/p21 activity. Cell Death Dis 8:e2766 (2017). WB ; Human . PubMed: 28471446