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    rp105-antibody-ab126267.pdf

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Immunology Innate Immunity Macrophage / Inflamm.
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Anti-RP105 antibody (ab126267)

  • Datasheet
  • SDS
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Western blot - Anti-RP105 antibody (ab126267)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RP105 antibody (ab126267)

Key features and details

  • Rabbit polyclonal to RP105
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG

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Secondary
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Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-RP105 antibody
    See all RP105 primary antibodies
  • Description

    Rabbit polyclonal to RP105
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 195-503 of Human RP105 (Q99467).

  • Positive control

    • HL60 whole cell lysate; CL15 xenograft tissue.
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 78.99% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Immunology
    • Innate Immunity
    • Macrophage / Inflamm.
    • Immunology
    • Adaptive Immunity
    • B Cells
    • CD
    • Immunology
    • Adaptive Immunity
    • B Cells
    • Non-CD
    • Microbiology
    • Protein
    • Human Protein
    • Defensin

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Positive Controls

    • HL-60 whole cell lysate (ab7914)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab126267 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
1/500 - 1/3000. Predicted molecular weight: 74 kDa.
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
Notes
WB
1/500 - 1/3000. Predicted molecular weight: 74 kDa.
IHC-P
1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
  • Tissue specificity

    Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
  • Sequence similarities

    Belongs to the Toll-like receptor family.
    Contains 19 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession Q99467 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 4064 Human
    • Omim: 602226 Human
    • SwissProt: Q99467 Human
    • Unigene: 87205 Human
    • Alternative names

      • CD180 antibody
      • CD180 antigen antibody
      • CD180_HUMAN antibody
      • F630107B15 antibody
      • LY64 antibody
      • Ly78 antibody
      • Lymphocyte antigen 64 antibody
      • lymphocyte antigen 64 radioprotective 105kDa antibody
      • lymphocyte antigen-64, radioprotective, 105kDa antibody
      • MGC126233 antibody
      • MGC126234 antibody
      • Radioprotective 105 kDa protein antibody
      • RP105 antibody
      see all

    Images

    • Western blot - Anti-RP105 antibody (ab126267)
      Western blot - Anti-RP105 antibody (ab126267)
      Anti-RP105 antibody (ab126267) at 1/1000 dilution + HL60 whole cell lysate at 30 µg

      Predicted band size: 74 kDa



      7.5% SDS PAGE
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RP105 antibody (ab126267)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RP105 antibody (ab126267)
      ab126267, at 1/500 dilution, staining RP105 in CL15 xenograft tissue by Immunohistochemistry.

    Protocols

    • Western blot protocols
    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab126267? Please let us know so that we can cite the reference in this datasheet.

    ab126267 has not yet been referenced specifically in any publications.

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