Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term.
Storage bufferpH: 7.40
Preservative: 0.01% Sodium azide
Concentration information loading...
PurityProtein A purified
Purification notesPurity > 95% (by SDS-PAGE)
Our Abpromise guarantee covers the use of ab111150 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IP||Use at an assay dependent concentration.|
|Functional Studies||Use at an assay dependent concentration. Induction of B cell proliferation.|
|Flow Cyt||Use a concentration of 2 µg/ml.
ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
FunctionMay cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells.
Tissue specificityExpressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells.
Sequence similaritiesBelongs to the Toll-like receptor family.
Contains 19 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Cellular localizationCell membrane.
- Information by UniProt
- CD180 antibody
- CD180 antigen antibody
- CD180_HUMAN antibody
ab111150 has not yet been referenced specifically in any publications.