Key features and details
- Rabbit polyclonal to RPA4 - C-terminal
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-RPA4 antibody - C-terminal
DescriptionRabbit polyclonal to RPA4 - C-terminal
SpecificityDetects endogenous levels of RPA4 protein.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
- HEK293T, Raw264.7 and PC12 whole cell lysate
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.097% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesPurity is > 95% (by SDS-PAGE).
Our Abpromise guarantee covers the use of ab200742 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent concentration. Predicted molecular weight: 29 kDa.|
FunctionFunctions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair; it does not support chromosomal DNA replication and cell cycle progression through S-phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
Tissue specificityPreferentially expressed in placental and colon mucosa. Widely expressed at intermediate or lower levels.
Cellular localizationNucleus. Localizes to DNA repair foci after DNA damage.
- Information by UniProt
- HSU24186 antibody
- MGC120333 antibody
- MGC120334 antibody
ab200742 has not yet been referenced specifically in any publications.