Product nameAnti-RPC39 antibody [EPR13200]
See all RPC39 primary antibodies
DescriptionRabbit monoclonal [EPR13200] to RPC39
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Recombinant fragment within Human RPC39 aa 1-200. The exact sequence is proprietary.
Database link: Q9H1D9
- BxPC-3, HeLa, A431 and HepG2 lysates.
Previously labelled as POLR3F.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 40% Glycerol, 59% PBS, 0.05% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab180501 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).|
FunctionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.
Sequence similaritiesBelongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
- Information by UniProt
- DNA directed RNA polymerase III 39 kDa polypeptide antibody
- DNA directed RNA polymerase III 39 kDa polypeptide F antibody
- DNA directed RNA polymerase III subunit F antibody
All lanes : Anti-RPC39 antibody [EPR13200] (ab180501) at 1/1000 dilution
Lane 1 : BxPC-3 lysate
Lane 2 : Hela lysate
Lane 3 : A431 lysate
Lane 4 : HepG2 lysate
Lysates/proteins at 20 µg per lane.
All lanes : Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 36 kDa
Additional bands at: 36 kDa. We are unsure as to the identity of these extra bands.
ab180501 has not yet been referenced specifically in any publications.