Key features and details
- Rabbit polyclonal to RPIA/PRI (FITC)
- Suitable for: WB
- Reacts with: Escherichia coli
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
Product nameAnti-RPIA/PRI antibody (FITC)
See all RPIA/PRI primary antibodies
DescriptionRabbit polyclonal to RPIA/PRI (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Escherichia coli
Recombinant full length protein corresponding to Escherichia coli RPIA/PRI aa 1-219.
MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAV SSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAAL TREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKL GGRPEYRQGVVTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFAN RGADVALIGTPDGVKTIVK
Database link: P0A7ZO
This product was previously labelled as RPIA
Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
Storage bufferpH: 7.40
Constituents: 49% PBS, 50% Glycerol, 0.03% Proclin 300
Concentration information loading...
PurityCaprylic Acid - Ammonium Sulfate precipitation
Our Abpromise guarantee covers the use of ab193545 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/50 - 1/600. Predicted molecular weight: 23 kDa.|
PathwayCarbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
Involvement in diseaseDefects in RPIA are the cause of ribose 5-phosphate isomerase deficiency (RPID) [MIM:608611]. A patient has been described with a deficiency of ribose 5-phosphate isomerase who presented with leukoencephalopathy and peripheral neuropathy. Proton magnetic resonance spectroscopy of the brain revealed a highly elevated level of the polyols ribitol and D-arabitol, which were subsequently also found in high concentrations in body fluids. Deficient activity of RPIA, one of the pentose phosphate pathway enzymes, has been demonstrated in fibroblasts.
Sequence similaritiesBelongs to the ribose 5-phosphate isomerase family.
- Information by UniProt
- EC 18.104.22.168 antibody
- MGC103524 antibody
- Phosphoriboisomerase A antibody
ab193545 has not yet been referenced specifically in any publications.