Anti-RPS19 antibody (ab187197)
Key features and details
- Rabbit polyclonal to RPS19
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RPS19 antibody
See all RPS19 primary antibodies -
Description
Rabbit polyclonal to RPS19 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Cow, Pig, Orangutan -
Immunogen
Recombinant full length protein corresponding to Human RPS19 aa 1 to the C-terminus.
Database link: P39019 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab187197 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 16 kDa.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 16 kDa. |
Target
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Function
Required for pre-rRNA processing and maturation of 40S ribosomal subunits. -
Tissue specificity
Higher level expression is seen in the colon carcinoma tissue than normal colon tissue. -
Involvement in disease
Defects in RPS19 are the cause of Diamond-Blackfan anemia type 1 (DBA1) [MIM:105650]. DBA1 is a form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. -
Sequence similarities
Belongs to the ribosomal protein S19e family. -
Cellular localization
Nucleus. Located more specifically in the nucleoli. - Information by UniProt
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Database links
- Entrez Gene: 6223 Human
- Omim: 603474 Human
- SwissProt: Q32PD5 Cow
- SwissProt: P39019 Human
- SwissProt: Q5R8M9 Orangutan
- SwissProt: Q29308 Pig
- Unigene: 438429 Human
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Alternative names
- 40S ribosomal protein S19 antibody
- DBA antibody
- DBA1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab187197 has not yet been referenced specifically in any publications.