Overview

  • Product name

    Anti-RPS19BP1/AROS antibody
    See all RPS19BP1/AROS primary antibodies
  • Description

    Rabbit polyclonal to RPS19BP1/AROS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human RPS19BP1/AROS aa 1-145.
    Sequence:

    MPGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDE NWFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVA RRVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKKH


    Database link: P39019

  • Positive control

    • WB: EC109 and HEK-293T cell lysate. IHC-P: Human colon cancer tissue.
  • General notes

     This product was previously labelled as RPS19BP1

     

Properties

Applications

Our Abpromise guarantee covers the use of ab236598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000.
IHC-P 1/20 - 1/200.

Target

  • Function

    Direct regulator of SIRT1. Enhances SIRT1-mediated deacetylation of p53/TP53, thereby participating in inhibition of p53/TP53-mediated transcriptional activity.
  • Tissue specificity

    Widely expressed (at protein level).
  • Sequence similarities

    Belongs to the AROS family.
  • Cellular localization

    Nucleus > nucleolus.
  • Information by UniProt
  • Database links

  • Alternative names

    • 40S ribosomal protein S19 binding protein 1 antibody
    • 40S ribosomal protein S19-binding protein 1 antibody
    • Active regulator of SIRT1 antibody
    • AROS antibody
    • AROS_HUMAN antibody
    • Homolog of mouse S19 binding protein antibody
    • Ribosomal protein S19 binding protein 1 antibody
    • RPS19 binding protein 1 antibody
    • RPS19-binding protein 1 antibody
    • RPS19BP1 antibody
    • S19BP antibody
    see all

Images

  • All lanes : Anti-RPS19BP1/AROS antibody (ab236598) at 1/1000 dilution

    Lane 1 : EC109 whole cell lysate
    Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate

    Secondary
    All lanes : Goat polyclonal to rabbit IgG at 1/15000 dilution
  • Paraffin-embedded human colon cancer tissue stained for RPS19BP1/AROS using ab236598 at 1/50 dilution in immunohistochemical analysis.

References

ab236598 has not yet been referenced specifically in any publications.

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