Key features and details
- β-Lactone antibiotic and antifungal agent
- CAS Number: 29066-42-0
- Purity: > 95%
- Soluble in ethanol and in DMSO
- Form / State: Solid
- Source: Scopulariopsis sp.
Product name(R,R)-Hymeglusin, antibiotic agent
Descriptionβ-Lactone antibiotic and antifungal agent
- Antibiotic 1233A
- Antibiotic F 244
- Antibiotic L-659-699
Biological descriptionβ-Lactone antibacterial and antifungal agent. Specific irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase (IC50 = 0.12 µM) in vitro and in vivo.
See similar compound
Chemical name(2E,4E,7R)-11-[(2R,3R)-3-(Hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol and in DMSO
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144274 has not yet been referenced specifically in any publications.