Overview

  • Product name

  • Description

    Rabbit polyclonal to RRAGC
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Sheep, Horse, Cow, Cat, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan, Giant Panda
  • Immunogen

    Synthetic peptide within Human RRAGC aa 349-399. The exact sequence is proprietary. (NP_071440.1).
    Database link: Q9HB90

  • Positive control

    • IP: HEK-293T whole cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab226199 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function

      Has guanine nucleotide-binding activity but weak intrinsic GTPase activity. Probably required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.
    • Sequence similarities

      Belongs to the GTR/RAG GTP-binding protein family.
    • Cellular localization

      Cytoplasm. Nucleus. Lysosome. Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.
    • Information by UniProt
    • Database links

    • Alternative names

      • AU041672 antibody
      • FLJ13311 antibody
      • GTPase interacting protein 2 antibody
      • GTPase-interacting protein 2 antibody
      • GTR2 antibody
      • MGC47404 antibody
      • OTTHUMP00000000548 antibody
      • Rag C antibody
      • Rag C protein antibody
      • RAGC antibody
      • Ras related GTP binding C antibody
      • Ras-related GTP-binding protein C antibody
      • RP23 29H22.4 antibody
      • RRAGC antibody
      • RRAGC_HUMAN antibody
      • TIB929 antibody
      • YGR163W antibody
      see all

    Images

    • RRAGC was immunoprecipitated from HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate (20% of IP loaded) with ab226199 at 6 µg per reaction. Western blot was performed from the immunoprecipitate using ab226199 at 1 µg/ml.

      Lane 1: ab226199 IP in HEK-293T whole cell lysate.

      Lane 2: Control IgG IP in HEK-293T whole cell lysate.

      Detection: Chemiluminescence with exposure time of 3 minutes.

    References

    ab226199 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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