(R,S)-Lenalidomide, Thalidomide analog, TNF-alpha inhibitor (ab142129)

Overview

  • Product name

    (R,S)-Lenalidomide, Thalidomide analog, TNF-alpha inhibitor
  • Description

    Thalidomide analog, TNF-α inhibitor
  • Biological description

    Thalidomide (ab120032) analog and TNF-α inhibitor. Potent antitumor and anti-inflammatory effects. Modulates and potentiates host immune responses against multiple myeloma. Active in vitro.
  • Purity

    > 98%
  • CAS Number

    191732-72-6
  • Chemical structure

    Chemical Structure

Properties

Associated products

References

This product has been referenced in:

  • Hickey CJ  et al. Lenalidomide-mediated enhanced translation of C/EBPa-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia. Blood 121:159-69 (2013). Read more (PubMed: 23100311) »
  • Shiheido H  et al. A phthalimide derivative that inhibits centrosomal clustering is effective on multiple myeloma. PLoS One 7:e38878 (2012). Read more (PubMed: 22761710) »
  • Rozewski DM  et al. Pharmacokinetics and tissue disposition of lenalidomide in mice. AAPS J 14:872-82 (2012). Read more (PubMed: 22956478) »

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