Overview

  • Product name

    Anti-rSec6 antibody [9H5]
    See all rSec6 primary antibodies
  • Description

    Mouse monoclonal [9H5] to rSec6
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Sheep, Rabbit, Chicken, Hamster, Cow, Dog, Human, Pig, Monkey
  • Immunogen

    Recombinant full length rSec6 protein (Rat)

  • General notes


    rSec6 is an 87 kDa rat homolog of yeast Sec6p, a protein involved in protein transport between the Golgi apparatus and the plasma membrane2. In yeast, Sec6p is part of a high molecular weight complex which includes Sec8p and Sec15p, that associates with the ras-like GTP binding protein Sec4p 2. An analogous 17S complex in rat brain was found to contain eight novel proteins, including rSec6 and rSec8, with a combined molecular weight of 734 kDa 3. Membrane associated rSec6/8 complex has been shown to coimmunoprecipitate with syntaxin, and is ubiquitously expressed, further ev idence that this complex is involved in the mammalian exocyst complex.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.2
  • Concentration information loading...
  • Purity

    Protein G purified
  • Primary antibody notes

    rSec6 is an 87 kDa rat homolog of yeast Sec6p, a protein involved in protein transport between the Golgi apparatus and the plasma membrane2. In yeast, Sec6p is part of a high molecular weight complex which includes Sec8p and Sec15p, that associates with the ras-like GTP binding protein Sec4p 2. An analogous 17S complex in rat brain was found to contain eight novel proteins, including rSec6 and rSec8, with a combined molecular weight of 734 kDa 3. Membrane associated rSec6/8 complex has been shown to coimmunoprecipitate with syntaxin, and is ubiquitously expressed, further ev idence that this complex is involved in the mammalian exocyst complex.
  • Clonality

    Monoclonal
  • Clone number

    9H5
  • Isotype

    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab69740 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250. Predicted molecular weight: 87 kDa.

Target

References

This product has been referenced in:

  • Fernández RM  et al. Cyclin D1 interacts and collaborates with Ral GTPases enhancing cell detachment and motility. Oncogene 30:1936-46 (2011). Read more (PubMed: 21242975) »
See 1 Publication for this product

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