Anti-RSRC1 antibody (ab106650)
Key features and details
- Rabbit polyclonal to RSRC1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-RSRC1 antibody -
Description
Rabbit polyclonal to RSRC1 -
Host species
Rabbit -
Specificity
Two isoforms of RSRC1 are known to exist; ab106650 will detect both. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
A 19 amino acid synthetic peptide near the C terminus of Human RSRC1 (NP_057709).
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Positive control
- WB: HepG2 cell lysate;
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab106650 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 39 kDa.
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Notes |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 39 kDa. |
Target
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Function
Plays a role in pre-mRNA splicing. Involved in both constitutive and alternative pre-mRNA splicing. May have a role in the recognition of the 3' splice site during the second step of splicing. -
Post-translational
modificationsPhosphorylated. -
Cellular localization
Nucleus. Nucleus speckle. Cytoplasm. Shuttles between the nucleus and cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 51319 Human
- Omim: 613352 Human
- SwissProt: Q96IZ7 Human
- Unigene: 591283 Human
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Alternative names
- 1200013F24Rik antibody
- Arginine/serine rich coiled coil 1 antibody
- Arginine/serine-rich coiled-coil protein 1 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab106650 has been referenced in 2 publications.
- Perez Y et al. RSRC1 mutation affects intellect and behaviour through aberrant splicing and transcription, downregulating IGFBP3. Brain 141:961-970 (2018). PubMed: 29522154
- McDaniel LD et al. Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma. PLoS Genet 13:e1006787 (2017). PubMed: 28545128