Key features and details
- Rabbit polyclonal to RST - C-terminal
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RST antibody - C-terminal
See all RST primary antibodies
DescriptionRabbit polyclonal to RST - C-terminal
SpecificityThis antibody detects endogenous levels of total RST protein.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human RST aa 528-540 (C terminal).
Database link: Q96S37
- HeLa and 293T cell lysates. Human liver cancer tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198791 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/25 - 1/100.|
|WB||1/200 - 1/1000. Predicted molecular weight: 59 kDa.|
FunctionRequired for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions.
Tissue specificityDetected in kidney (at protein level). Detected in fetal and adult kidney. Detected in epithelial cells of proximal tubules in renal cortex.
Involvement in diseaseDefects in SLC22A12 are a cause of renal hypouricemia (RH) [MIM:220150]. Patients have low serum urate levels, due to defects in renal urate re-absorption and high urinary urate excretion. Patients often appear asymptomatic, but may be subject to exercise-induced acute renal failure (ARF), chronic renal dysfunction and uric acid urolithiasis.
Sequence similaritiesBelongs to the major facilitator superfamily. Organic cation transporter family.
Cellular localizationCell membrane. Detected in the luminal membrane of the epithelium of renal proximal tubules.
- Information by UniProt
- Organic anion transporter 4-like protein antibody
- Renal-specific transporter antibody
- RST antibody
ab198791 has not yet been referenced specifically in any publications.