Product nameAnti-RTKN/Rhotekin antibody
See all RTKN/Rhotekin primary antibodies
DescriptionRabbit polyclonal to RTKN/Rhotekin
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human RTKN/Rhotekin aa 304-563.
PLCMTQPTASGTLRVQQAGEMQNWAQVHGVLKGTNLFCYRQPEDADTGEE PLLTIAVNKETRVRAGELDQALGRPFTLSISNQYGDDEVTHTLQTESREA LQSWMEALWQLFFDMSQWKQCCDEIMKIETPAPRKPPQALAKQGSLYHEM AIEPLDDIAAVTDILTQREGARLETPPPWLAMFTDQPALPNPCSPASVAP APDWTHPLPWGRPRTFSLDAVPPDHSPRARSVAPLPPQRSPRTRGLCSKG QPRTWLQSPV
Database link: Q9BST9
- IHC-P: Human prostate cancer and testis tissues. WB: A431, HepG2, MCF-7 and mouse brain lysates.
This product was previously labelled as RTKN
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab234866 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
|WB||Use a concentration of 4.66 µg/ml. Predicted molecular weight: 63 kDa.|
FunctionMediates Rho signaling to activate NF-kappa-B and may confer increased resistance to apoptosis to cells in gastric tumorigenesis. May play a novel role in the organization of septin structures.
Tissue specificityHighly expressed in prostate, moderately in kidney, heart, brain, spleen, testis, placenta, small intestine, pancreas, skeletal muscle and peripheral blood leukocytes, and weakly in ovary, colon and thymus. Weakly expressed in all normal cell lines tested. Overexpressed in various cancer cell lines.
Sequence similaritiesContains 1 PH domain.
Contains 1 REM (Hr1) repeat.
- Information by UniProt
- Rhotekin antibody
- Rtkn antibody
- RTKN_HUMAN antibody
- RTKN1 antibody
All lanes : Anti-RTKN/Rhotekin antibody (ab234866) at 4.66 µg/ml
Lane 1 : A431 cell lysate
Lane 2 : HepG2 cell lysate
Lane 3 : MCF-7 cell lysate
Lane 4 : Mouse brain lysate
All lanes : Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 63 kDa
Paraffin-embedded human testis tissue stained for RTKN/Rhotekin using ab234866 at 1/100 dilution in immunohistochemical analysis.
Paraffin-embedded human prostate cancer tissue stained for RTKN/Rhotekin using ab234866 at 1/100 dilution in immunohistochemical analysis.
ab234866 has not yet been referenced specifically in any publications.