Overview

  • Product name

    Rubratoxin A, PP2A inhibitor
  • Description

    Potent, selective, competitive PP2A inhibitor
  • Biological description

    Potent, selective, competitive PP2A inhibitor (Ki = 28.7 nM). Rubratoxin B analog. Induces caspase-dependent decrease in cell viability. Shows antitumor effects in vivo.
  • Purity

    > 95%
  • CAS Number

    22467-31-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    9-((3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl)-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona(c)furan-6,7-dicarboxylic anhydride
  • Molecular weight

    520.53
  • Molecular formula

    C26H32O11
  • PubChem identifier

    56840856
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol in and DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CCCCCC[C@@H](C1[C@@H](C2=C(CC(CC3=C1C(=O)OC3O)[C@@H](C4CC=CC(=O)O4)O)C(=O)OC2=O)O)O
  • Source

    Penicillium sp.

  • Research areas

References

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