Overview

  • Product name

    Rubrofusarin, tyrosinase inhibitor
  • Description

    Moderate tyrosinase inhibitor
  • Biological description

    Moderate tyrosinase inhibitor (IC50 = 65.6 μM). Shows antiestrogenic effects. Shows antimycobacterial effects in vivo.
  • Purity

    > 98%
  • CAS Number

    3567-00-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5,6-Dihydroxy-8-methoxy-2-methylbenzo[g]chromen-4-one
  • Molecular weight

    272.25
  • Molecular formula

    C15H12O5
  • PubChem identifier

    72537
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1=CC(=O)C2=C(O1)C=C3C=C(C=C(C3=C2O)O)OC
  • Source

    Fusarium graminearum

  • Research areas

References

This product has been referenced in:

  • Huang HB  et al. Three dimeric naphtho-?-pyrones from the mangrove endophytic fungus Aspergillus tubingensis isolated from Pongamia pinnata. Planta Med 76:1888-91 (2010). Read more (PubMed: 20506081) »
  • Frandsen RJ  et al. Methylenetetrahydrofolate reductase activity is involved in the plasma membrane redox system required for pigment biosynthesis in filamentous fungi. Eukaryot Cell 9:1225-35 (2010). Read more (PubMed: 20543064) »
  • El-Halawany AM  et al. Estrogenic and anti-estrogenic activities of Cassia tora phenolic constituents. Chem Pharm Bull (Tokyo) 55:1476-82 (2007). Read more (PubMed: 17917292) »

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