Rufloxacin hydrochloride (MF-934), Fluoroquinolone antibiotic agent (ab143450)

Overview

  • Product name

    Rufloxacin hydrochloride (MF-934), Fluoroquinolone antibiotic agent
  • Description

    Fluoroquinolone broad spectrum antibiotic
  • Biological description

    Fluoroquinolone broad spectrum antibiotic. Selective DNA gyrase inhibitor. Inhibits B-cell differentiation. Shows more potent antimicrobial activity than Nalidixic acid (ab143137). Orally active.
  • Purity

    > 98%
  • CAS Number

    106017-08-7
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    9-Fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid hydrochloride
  • Molecular weight

    399.87
  • Molecular formula

    C17H18FN3O3S.HCl
  • PubChem identifier

    176015
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 5 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CN1CCN(CC1)C2=C(C=C3C4=C2SCCN4C=C(C3=O)C(=O)O)F.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Ravizzola G  et al. Rufloxacin (MF-934): in vitro and in vivo antibacterial activity. Drugs Exp Clin Res 15:11-5 (1989). Read more (PubMed: 2743869) »
  • Segre G  et al. A new tricyclic fluoroquinolone, rufloxacin (MF-934), with interesting antibacterial and pharmacokinetic characteristics. Drugs Exp Clin Res 14:747-54 (1988). Read more (PubMed: 3253051) »
  • Gismondo MR  et al. Impact of rufloxacin and ciprofloxacin on the intestinal microflora in a germ-free mice model. Chemotherapy 41:281-8 (0). Read more (PubMed: 7555209) »

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