Rugulosin ((+)-Rugulosin), RNA polymerase inhibitor (ab144351)

Overview

  • Product name

    Rugulosin ((+)-Rugulosin), RNA polymerase inhibitor
  • Description

    Mycotoxin. RNA polymerase inhibitor.
  • Alternative names

    • (+)-Rugulosin
  • Biological description

    Mycotoxin. RNA polymerase inhibitor. Shows weak hepatocarcinogenic effects in vivo. Shows antibacterial and insecticidal effects. Orally active.
  • Purity

    > 95%
  • CAS Number

    23537-16-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Mori H  et al. Genotoxicity of a variety of mycotoxins in the hepatocyte primary culture/DNA repair test using rat and mouse hepatocytes. Cancer Res 44:2918-23 (1984). Read more (PubMed: 6722817) »
  • Ueno Y  et al. Chronic toxicity and hepatocarcinogenicity of (+) rugulosin, an anthraquinoid mycotoxin from penicillium species: preliminary surveys in mice. J Toxicol Sci 5:295-302 (1980). Read more (PubMed: 7218376) »
  • Tashiro F  et al. Inhibitory effects of carcinogenic mycotoxins on deoxyribonucleic acid-dependent ribonucleic acid polymerase and ribonuclease H. Appl Environ Microbiol 38:191-6 (1979). Read more (PubMed: 117749) »

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