Key features and details
- Rabbit polyclonal to RUNX1T1/ETO/CDR
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-RUNX1T1/ETO/CDR antibody
See all RUNX1T1/ETO/CDR primary antibodies
DescriptionRabbit polyclonal to RUNX1T1/ETO/CDR
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide corresponding to Human RUNX1T1/ETO/CDR. (Near the C terminal; NP_001185554).
Database link: Q06455-2
- Human thyroid cancer tissue.
This product was previously labelled as RUNX1T1 / ETO
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab200392 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/25 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionTranscription regulator that excerts its function by binding to histone deacetylases and transcription factors. Can repress transactivation mediated by TCF12.
Tissue specificityMost abundantly expressed in brain. Lower levels in lung, heart, testis and ovary.
Involvement in diseaseNote=A chromosomal aberration involving RUNX1T1 is a cause of acute myeloid leukemia (AML-M2). Translocation t(8;21)(q22;q22) with RUNX1/AML1.
Defects in RUNX1T1 may be a cause of colorectal cancer (CRC) [MIM:114500].
Sequence similaritiesBelongs to the CBFA2T family.
Contains 1 MYND-type zinc finger.
Contains 1 TAFH (NHR1) domain.
DomainThe TAFH domain mediates interaction with transcription regulators.
- Information by UniProt
- Acute myelogenous leukemia 1 translocation 1 cyclin D related antibody
- Acute myelogenous leukemia 1 translocation 1 protein antibody
- AML1 MTG8 antibody
ab200392 has not yet been referenced specifically in any publications.