Anti-RSUME antibody (ab91555)
Key features and details
- Rabbit polyclonal to RSUME
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
Overview
-
Product name
Anti-RSUME antibody -
Description
Rabbit polyclonal to RSUME -
Host species
Rabbit -
Specificity
At least four isoforms of RSUME are known to exist; this antibody will only detect the largest isoform. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat -
Immunogen
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab91555 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 31 kDa.
|
Notes |
---|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 31 kDa. |
Target
-
Function
Enhances the sumoylation of a number of proteins including HIF1A, PIAS and I-kappa-B, through direct interaction with UBC9. Has no effect on ubiquitination. -
Tissue specificity
Expressed in a wide number of tissues with highest expression in cerebellum, pituitary, heart, kidney, liver, stomach, pancreas, prostate and spleen. Low levels in thalamus, spinal cord, esophagus, thymus, lung and peripheral blood leukocytes. -
Sequence similarities
Contains 1 RWD domain. -
Domain
The RWD domain is required for the sumoylation enhancement activity. -
Cellular localization
Nucleus. Cytoplasm. Colocalizes with UBC9/UBE2I in nuclear spots. - Information by UniProt
-
Database links
- Entrez Gene: 65026 Rat
- SwissProt: P0C7N0 Rat
- Unigene: 54470 Rat
-
Alternative names
- DKFZp566K023 antibody
- RSUME antibody
- RWD containing sumoylation enhancer antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (1)
ab91555 has been referenced in 1 publication.
- Chen X et al. Knockdown of RWD domain containing 3 inhibits the malignant phenotypes of glioblastoma cells via inhibition of phosphoinositide 3-kinase/protein kinase B signaling. Exp Ther Med 16:384-393 (2018). PubMed: 29977365