Key features and details
- CD45 tyrosine phosphatase inhibitor
- CAS Number:
- Purity: > 95%
- Soluble in DMSO to 25 mM
- Form / State: Solid
- Source: Synthetic
Product nameRWJ-60475 (AM)3, CD45 tyrosine phosphatase inhibitor
DescriptionCD45 tyrosine phosphatase inhibitor
Biological descriptionCD45 tyrosine phosphatase inhibitor (IC50 = 2 μM). Cell permeable. Inhibits ADP induced platelet aggregation and IL-2 production in vitro.
Chemical name2-(4-Bromophenoxy)-5-nitrophenylhydroxymethylphosphonic acid tris(acetoxymethyl) ester
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141729 has been referenced in 1 publication.
- Marchesi S et al. DEPDC1B coordinates de-adhesion events and cell-cycle progression at mitosis. Dev Cell 31:420-33 (2014). PubMed: 25458010