Overview

  • Product name

  • Description

    Rabbit polyclonal to RXFP1
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ANGPT2 (47%).
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Human RXFP1 (C terminal).
    Database link: NP_067647.2

  • Positive control

    • Human uterus, endometrium tissue.
  • General notes

     This product was previously labelled as GPCR LGR7

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab140903 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 12 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
  • Tissue specificity

    Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
    Contains 1 LDL-receptor class A domain.
    Contains 9 LRR (leucine-rich) repeats.
    Contains 1 LRRNT domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Gm1018 antibody
    • Leucine rich repeat containing G protein coupled receptor 7 antibody
    • Leucine-rich repeat-containing G-protein coupled receptor 7 antibody
    • LGR 7 antibody
    • LGR7 antibody
    • LGR7.1 antibody
    • LGR7.10 antibody
    • LGR7.2 antibody
    • MGC138347 antibody
    • MGC142177 antibody
    • Relaxin family peptide receptor 1 antibody
    • Relaxin receptor 1 antibody
    • Relaxin/insulin like family peptide receptor 1 antibody
    • RXFP 1 antibody
    • RXFP1 antibody
    • RXFP1_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human uterus endometrium tissue labelling RXFP1 with ab140903 at 12µg/ml.

References

ab140903 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (Frozen sections)
Sample
Mouse Tissue sections (Testis, postnatal day 6)
Permeabilization
Yes - 0.1% Triton X-100 in PBS
Specification
Testis, postnatal day 6
Blocking step
BSA as blocking agent for 30 minute(s) · Concentration: 3% · Temperature: 20°C
Fixative
Paraformaldehyde

Mr. Bryan Niedenberger

Verified customer

Submitted Aug 18 2019

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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