Key features and details
- Rabbit polyclonal to RXFP1 - Extracellular domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-RXFP1 antibody - Extracellular domain
See all RXFP1 primary antibodies
DescriptionRabbit polyclonal to RXFP1 - Extracellular domain
SpecificityBLAST analysis of the peptide immunogen showed no homology with other human proteins, except GPR22 (58%).
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Horse, Cow, Dog, Pig, Monkey, Gorilla, Orangutan
Synthetic peptide within Human RXFP1 (N terminal). The exact sequence is proprietary. The peptide corresponds to 19 amino acids from the N-terminal extracellular domain. (NP_067647.2)
Database link: Q9HBX9
- Human adrenal medulla tissue.
This product was previously labelled as GPCR LGR7
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab188759 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 40 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionReceptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP.
Tissue specificityExpressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Contains 1 LDL-receptor class A domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.
Cellular localizationCell membrane.
- Information by UniProt
- Gm1018 antibody
- Leucine rich repeat containing G protein coupled receptor 7 antibody
- Leucine-rich repeat-containing G-protein coupled receptor 7 antibody
ab188759 has not yet been referenced specifically in any publications.