Anti-RXFP1 antibody - N-terminal (ab188746)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-RXFP1 antibody - N-terminal
See all RXFP1 primary antibodies -
Description
Rabbit polyclonal to RXFP1 - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Horse, Cow, Dog, Pig, Monkey, Gorilla, Orangutan
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Immunogen
Synthetic peptide corresponding to Human RXFP1 (extracellular). 20 amino acid peptide from N-terminal extracellular domain. NP_067647.2.
Database link: Q9HBX9 -
Positive control
- Human uterus endometrium tissue.
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General notes
This product was previously labelled as GPCR LGR7
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab188746 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 10 - 13 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. -
Tissue specificity
Expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. Not detected in spleen. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Contains 1 LDL-receptor class A domain.
Contains 9 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 532277 Cow
- Entrez Gene: 100855494 Dog
- Entrez Gene: 101125189 Gorilla
- Entrez Gene: 100069240 Horse
- Entrez Gene: 59350 Human
- Entrez Gene: 381489 Mouse
- Entrez Gene: 100173672 Orangutan
- Entrez Gene: 100127453 Pig
see all -
Alternative names
- Gm1018 antibody
- Leucine rich repeat containing G protein coupled receptor 7 antibody
- Leucine-rich repeat-containing G-protein coupled receptor 7 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-RXFP1 antibody - N-terminal (ab188746)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human uterus endometrium tissue labeling RXFP1 with ab188746 at 10 µg/ml.
Protocols
References
ab188746 has not yet been referenced specifically in any publications.
