Key features and details
- Rabbit polyclonal to RYR-3
- Reacts with: Recombinant fragment
- Isotype: IgG
Product nameAnti-RYR-3 antibody
DescriptionRabbit polyclonal to RYR-3
Species reactivityReacts with: Recombinant fragment
Predicted to work with: Human
Synthetic peptide corresponding to Human RYR-3 (C terminal).
Previously labelled as Ryanodine Receptor 3.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS
Concentration information loading...
PurityImmunogen affinity purified
FunctionCommunication between transverse-tubules and sarcoplasmic reticulum. Contraction of skeletal muscle is triggered by release of calcium ions from SR following depolarization of T-tubules.
Tissue specificityBrain, skeletal muscle, placenta and possibly liver and kidney. In brain, highest levels are found in the cerebellum, hippocampus, caudate nucleus and amygdala, with lower levels in the corpus callosum, substantia nigra and thalamus.
Sequence similaritiesBelongs to the ryanodine receptor (TC 1.A.3.1) family. RYR3 subfamily.
Contains 3 B30.2/SPRY domains.
Contains 1 EF-hand domain.
Contains 5 MIR domains.
- Information by UniProt
- Brain ryanodine receptor calcium release channel antibody
- Brain ryanodine receptor-calcium release channel antibody
- Brain type ryanodine receptor antibody
ab56000 has been referenced in 1 publication.
- Nensa FM et al. Amyloid beta a4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain. Mol Cell Proteomics 13:475-88 (2014). PubMed: 24284412