Key features and details
- Major metabolite of nicotine in humans. Activates, and desensitizes neuronal nicotinic acetylcholine receptors.
- CAS Number: 486-56-6
- Form / State: Solid
- Source: Synthetic
Product name(S)-Cotinine, nicotine metabolite
DescriptionMajor metabolite of nicotine in humans. Activates, and desensitizes neuronal nicotinic acetylcholine receptors.
Major metabolite of nicotine in humans. Displays cognition-enhancing effects in vivo; reduces amyloid β (Aβ) aggregation and improves memory in an Alzheimer's disease mouse model. Activates a subpopulation of α3/α6β2 nAChRs in monkey striatum.
Storage instructionsStore at +4°C.
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To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab144813 has not yet been referenced specifically in any publications.