Overview

  • Product name

    (S)-Sulpiride, D2-like dopamine antagonist
  • Description

    D2-like dopamine antagonist. Active enantiomer.
  • Biological description

    Selective D2-like dopamine antagonist (Ki values are ~ 0.015, ~ 0.013, and 1 μM at D2, D3, and D4 receptors, respectively). Active enantiomer of Sulpiride (ab120578). Antipsychotic and prokinetic agent.
  • Purity

    > 99%
  • CAS Number

    23672-07-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Merlo S  et al. Distinct effects of pramipexole on the proliferation of adult mouse sub-ventricular zone-derived cells and the appearance of a neuronal phenotype. Neuropharmacology 60:892-900 (2011). Read more (PubMed: 21272591) »
  • Ichikawa J & Meltzer HY R(+)-8-OH-DPAT, a serotonin(1A) receptor agonist, potentiated S(-)-sulpiride-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens but not striatum. J Pharmacol Exp Ther 291:1227-32 (1999). Read more (PubMed: 10565846) »
  • Zuccato E  et al. The effects of S(-) and R(+) sulpiride, metoclopramide, cisapride and domperidone on the small intestine suggest DA2-receptors are involved in the control of small intestinal transit time in rats. Pharmacol Res 26:179-85 (1992). Read more (PubMed: 1409258) »
See 1 Publication for this product

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