Key features and details
- D2-like dopamine antagonist. Active enantiomer.
- CAS Number: 23672-07-3
- Soluble in DMSO to 100 mM and in ethanol to 25 mM (with warming)
- Form / State: Solid
- Source: Synthetic
Product name(S)-Sulpiride, D2-like dopamine antagonist
DescriptionD2-like dopamine antagonist. Active enantiomer.
Selective D2-like dopamine antagonist (Ki values are ~ 0.015, ~ 0.013, and 1 μM at D2, D3, and D4 receptors, respectively). Active enantiomer of Sulpiride (ab120578). Antipsychotic and prokinetic agent.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 25 mM (with warming)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120579 has been referenced in 1 publication.
- Nimitvilai S et al. Effects of monoamines on the intrinsic excitability of lateral orbitofrontal cortex neurons in alcohol-dependent and non-dependent female mice. Neuropharmacology 137:1-12 (2018). PubMed: 29689260