(S)-WAY 100135, 5-HT1A receptor antagonist (ab146821)
Key features and details
- Potent, selective 5-HT1A receptor antagonist
- CAS Number: 149007-54-5
- Purity: > 99%
- Soluble in water to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
(S)-WAY 100135, 5-HT1A receptor antagonist -
Description
Potent, selective 5-HT1A receptor antagonist -
Purity
> 99% -
CAS Number
149007-54-5 -
Chemical structure
Properties
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Chemical name
(S)-(-)-N-tert-Butyl-3-(4-(2-methoxyphenyl)piperazin-1-yl)-2-phenylpropanamide dihydrochloride -
Molecular weight
468.47 -
Molecular formula
C24H33N3O2.2HCl -
PubChem identifier
14801907 -
Storage instructions
Store at room temperature. -
Solubility overview
Soluble in water to 10 mM and in DMSO to 100 mM -
Handling
Toxic, refer to SDS for further information
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(C)(C)NC(=O)[C@H](CN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3.Cl.Cl -
Source
Synthetic
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (2)
ab146821 has been referenced in 2 publications.
- Carli M et al. (S)-WAY 100135, a 5-HT1A receptor antagonist, prevents the impairment of spatial learning caused by intrahippocampal scopolamine. Eur J Pharmacol 283:133-9 (1995). PubMed: 7498302
- Rodgers RJ & Cole JC Anxiolytic-like effect of (S)-WAY 100135, a 5-HT1A receptor antagonist, in the murine elevated plus-maze test. Eur J Pharmacol 261:321-5 (1994). PubMed: 7813555