Overview

  • Product name

    Anti-S100 antibody [D28-E]
    See all S100 primary antibodies
  • Description

    Rabbit monoclonal [D28-E] to S100
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Fr, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human S100 (C terminal).

  • Epitope

    Antibody recognizes the epitope located between Val55 - Glu69
  • Positive control

    • Human neurofibroma, skin melanoma, cutaneous malignant melanoma, and breast tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab136629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent concentration.
IHC-P 1/100 - 1/200.

Target

  • Function

    Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.
  • Tissue specificity

    Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.
  • Sequence similarities

    Belongs to the S-100 family.
    Contains 2 EF-hand domains.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Bpb antibody
    • NEF antibody
    • Protein S100-A1 antibody
    • S-100 protein alpha chain antibody
    • S-100 protein subunit alpha antibody
    • S100 alpha antibody
    • S100 beta antibody
    • S100 calcium binding protein A1 antibody
    • S100 calcium binding protein B antibody
    • S100 calcium-binding protein A1 antibody
    • S100 protein alpha polypeptide antibody
    • S100A antibody
    • s100a1 antibody
    • S100B antibody
    • S100beta antibody
    • S10A1_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human neurofibroma tissue labelling S100 with ab136629 antibody at 1/100 diltution.
  • Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human skin melanoma tissue labelling S100 with ab136629 antibody at 1/100 diltution.
  • Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human breast tissue labelling S100 with ab136629 antibody at 1/100 diltution.
  • Immunohistochemical analysis of formalin fixed, paraffin embedded human cutaneous malignant melanoma tissue labeling S100 with ab136629.

References

ab136629 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab136629.
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