Anti-S100 antibody [D28-E] (ab136629)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)

Key features and details

  • Rabbit monoclonal [D28-E] to S100
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG

Overview

  • Product name

    Anti-S100 antibody [D28-E]
    See all S100 primary antibodies

  • Description

    Rabbit monoclonal [D28-E] to S100

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Synthetic peptide corresponding to Human S100 (C terminal).

  • Epitope

    Antibody recognizes the epitope located between Val55 - Glu69

  • Positive control

    • Human neurofibroma, skin melanoma, cutaneous malignant melanoma, and breast tissues.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab136629 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
1/100 - 1/200.
Notes
IHC-P
1/100 - 1/200.

Target

  • Function

    Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites.

  • Tissue specificity

    Highly prevalent in heart. Also found in lesser quantities in skeletal muscle and brain.

  • Sequence similarities

    Belongs to the S-100 family.
    Contains 2 EF-hand domains.

  • Cellular localization

    Cytoplasm.
  • Information by UniProt

  • Database links

    • Alternative names

      • Bpb antibody
      • NEF antibody
      • Protein S100-A1 antibody
      • S-100 protein alpha chain antibody
      • S-100 protein subunit alpha antibody
      • S100 alpha antibody
      • S100 beta antibody
      • S100 calcium binding protein A1 antibody
      • S100 calcium binding protein B antibody
      • S100 calcium-binding protein A1 antibody
      • S100 protein alpha polypeptide antibody
      • S100A antibody
      • s100a1 antibody
      • S100B antibody
      • S100beta antibody
      • S10A1_HUMAN antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
      Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human neurofibroma tissue labelling S100 with ab136629 antibody at 1/100 diltution.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
      Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human skin melanoma tissue labelling S100 with ab136629 antibody at 1/100 diltution.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
      Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human breast tissue labelling S100 with ab136629 antibody at 1/100 diltution.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-S100 antibody [D28-E] (ab136629)

      Immunohistochemical analysis of formalin fixed, paraffin embedded human cutaneous malignant melanoma tissue labeling S100 with ab136629.

    References (0)

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    ab136629 has not yet been referenced specifically in any publications.

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