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  1. Link

    s100-beta-peptide-ab30380.pdf

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S100 beta peptide (ab30380)

  • Datasheet
Submit a review Submit a question References (1)

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Promotion Information

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Key features and details

  • Purity: = 92% HPLC
  • Suitable for: Blocking

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Description

  • Product name

    S100 beta peptide
    See all S100 beta proteins and peptides
  • Purity

    = 92 % HPLC.
    Purified on a Reversed-Phase HPLC column and quality and characterized by mass spec. The purity of these peptides is checked by analytical HPLC and calculated by considering the area under the peptide peak as a percentage of areas under all peaks.
  • Animal free

    No
  • Nature

    Synthetic

Specifications

Our Abpromise guarantee covers the use of ab30380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituent: PBS

General Info

  • Alternative names

    • NEF
    • Protein S100 B
    • Protein S100-B
    • S 100 calcium binding protein beta chain
    • S 100 protein beta chain
    • S-100 protein beta chain
    • S-100 protein subunit beta
    • S100
    • S100 calcium binding protein beta (neural)
    • S100 calcium-binding protein B
    • S100 protein beta chain
    • S100B
    • S100B_HUMAN
    • S100beta
    see all
  • Function

    Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
  • Tissue specificity

    Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
  • Sequence similarities

    Belongs to the S-101 family.
    Contains 2 EF-hand domains.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Target information above from: UniProt accession P04271 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

  • Datasheet download

    Download

References (1)

Publishing research using ab30380? Please let us know so that we can cite the reference in this datasheet.

ab30380 has been referenced in 1 publication.

  • Koeppen AH  et al. Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation. Acta Neuropathol Commun 4:46 (2016). PubMed: 27142428

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