Overview

  • Product name

  • Description

    Rabbit polyclonal to S100A11
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein corresponding to Human S100A11.
    Database link: P31949

  • Positive control

    • BxPC3, BT474, LOVO, 22RV1, SKOV3 and THP1 cell extracts.

Properties

Applications

Our Abpromise guarantee covers the use of ab187180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 11 kDa.

Target

  • Function

    Facilitates the differentiation and the cornification of keratinocytes.
  • Sequence similarities

    Belongs to the S-100 family.
    Contains 2 EF-hand domains.
  • Post-translational
    modifications

    Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Calgizzarin antibody
    • Epididymis secretory protein Li 43 antibody
    • HEL S 43 antibody
    • Metastatic lymph node gene 70 protein antibody
    • MLN 70 antibody
    • MLN70 antibody
    • Protein S100 A11 antibody
    • Protein S100-A11 antibody
    • Protein S100-A11, N-terminally processed antibody
    • Protein S100-C antibody
    • Protein S100A11 antibody
    • Protein S100C antibody
    • S100 A11 antibody
    • S100 calcium binding protein A11 antibody
    • S100 calcium-binding protein A11 (calgizzarin) antibody
    • S100 calcium-binding protein A11 antibody
    • S100a11 antibody
    • S100C antibody
    • S10AB_HUMAN antibody
    see all

Images

  • All lanes : Anti-S100A11 antibody (ab187180) at 1/500 dilution

    Lane 1 : BxPC3 cell extract
    Lane 2 : BT474 cell extract
    Lane 3 : LOVO cell extract
    Lane 4 : 22RV1 cell extract
    Lane 5 : SKOV3 cell extract
    Lane 6 : THP1 cell extract

    Predicted band size: 11 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human stomach cancer tissue labelling S100A11 with ab187180 at 1/200. Magnification: 400x.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human lung cancer tissue labelling S100A11 with ab187180 at 1/200. Magnification: 400x.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney cancer tissue labelling S100A11 with ab187180 at 1/200. Magnification: 400x.
  • Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab187180. Blue DAPI for nuclear staining.

References

ab187180 has not yet been referenced specifically in any publications.

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