Overview

  • Product name

  • Description

    Rabbit polyclonal to S100A14
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow, Pig
  • Immunogen

    Recombinant fragment within Human S100A14 (internal sequence). The exact sequence is proprietary.
    Database link: Q9HCY8

  • Positive control

    • WB: MCF7 whole cell extract.
  • General notes

     This product was previously labelled as S100 calcium binding protein A14

     

Properties

Applications

Our Abpromise guarantee covers the use of ab226775 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 12 kDa.

Target

  • Function

    Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
  • Tissue specificity

    Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
  • Sequence similarities

    Belongs to the S-100 family.
    Contains 1 EF-hand domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • BCMP84 antibody
    • Protein S100-A14 antibody
    • S100 calcium binding protein A14 antibody
    • S100 calcium-binding protein A14 antibody
    • S100a14 antibody
    • S100A15 antibody
    • S10AE_HUMAN antibody
    • S114 antibody
    see all

Images

  • All lanes : Anti-S100A14 antibody (ab226775) at 1/1000 dilution

    Lane 1 : MCF7 (human breast adenocarcinoma cell line) whole cell extract
    Lane 2 : MCF7 (human breast adenocarcinoma cell line) treated with PMA (phorbol 12-myristate 13-acetate), whole cell extract

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 12 kDa



    15% SDS-PAGE gel.

References

ab226775 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab226775.
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