Overview

  • Product name

  • Description

    Rabbit polyclonal to S100A14
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human S100A14 aa 1-104.
    Sequence:

    MGQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKETLTPSELRDLV TQQLPHLMPSNCGLEEKIANLGSCNDSKLEFRSFWELIGEAAKSVKLERP VRGH


    Database link: Q9HCY8

  • Positive control

    • IHC-P: Human skin tissue.
  • General notes

     This product was previously labelled as S100 calcium binding protein A14

     

Properties

Applications

Our Abpromise guarantee covers the use of ab230279 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Function

    Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
  • Tissue specificity

    Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
  • Sequence similarities

    Belongs to the S-100 family.
    Contains 1 EF-hand domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • BCMP84 antibody
    • Protein S100-A14 antibody
    • S100 calcium binding protein A14 antibody
    • S100 calcium-binding protein A14 antibody
    • S100a14 antibody
    • S100A15 antibody
    • S10AE_HUMAN antibody
    • S114 antibody
    see all

Images

  • Paraffin-embedded human skin tissue stained for S100A14 using ab230279 at 1/100 dilution in immunohistochemical analysis.

References

ab230279 has not yet been referenced specifically in any publications.

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There are currently no Customer reviews or Questions for ab230279.
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