Product nameAnti-S1P antibody - C-terminal
See all S1P primary antibodies
DescriptionRabbit polyclonal to S1P - C-terminal
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat, Chinese hamster
Recombinant fragment corresponding to Human S1P aa 803-1052 (C terminal).
ITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDD SHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEG NHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKL LSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTI PVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV
Database link: Q14703
- WB: Mouse kidney tissue lysate. IHC-P: Human lung and small intestine tissues.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab224618 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
|WB||1/1000 - 1/5000. Detects a band of approximately 118 kDa (predicted molecular weight: 118 kDa).|
RelevanceS1P (also known as MBTPS1,SKI1), was first discovered as one of two enzymes that cleave the sterol regulatory binding proteins (SREBPs), in the case of S1P at “site-1,” a hydrophillic loop extending into the lumen of the ER. The MBTPS1 domain structure contains a signal sequence followed by a propeptide domain, a catalytic domain, a transmembrane domain and a cytoplasmic domain.
Cellular localizationEndoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein.
- kexin isozyme 1 antibody
- KIAA0091 antibody
- MBTPS1 antibody
Paraffin-embedded human small intestine tissue stained for S1P using ab224618 at 1/100 dilution in immunohistochemical analysis.
Paraffin-embedded human lung tissue stained for S1P using ab224618 at 1/100 dilution in immunohistochemical analysis.
Anti-S1P antibody - C-terminal (ab224618) at 1/1000 dilution + Mouse kidney tissue lysate
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 118 kDa
Observed band size: 118 kDa
ab224618 has not yet been referenced specifically in any publications.