Overview

  • Product name

  • Description

    Rabbit polyclonal to S31
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except HTR1F (65%).
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Horse, Chicken, Guinea pig, Cow, Turkey, Chimpanzee, Lizard, Monkey, Zebrafish, Gorilla, Opossum, Orangutan, House sparrow, Bat, Elephant
  • Immunogen

    Synthetic peptide corresponding to Human S31 (intracellular).

  • Positive control

    • Human skin and kidney tissues.
  • General notes

    Previously labelled as 5HT1E Receptor. 

Properties

Applications

Our Abpromise guarantee covers the use of ab140506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Relevance

    This is one of the several different receptors for 5-HT, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. The 5-HT1E receptor is expressed in human cortex, caudate, putamen, and amygdala, as well as in dorsal root ganglia and in coronary artery. ESTs have been isolated from human brain cancer libraries.
  • Cellular localization

    Cell Membrane, Multi-pass membrane protein.
  • Database links

  • Alternative names

    • 5 HT1E antibody
    • 5 hydroxytryptamine (serotonin) receptor 1E antibody
    • 5 hydroxytryptamine (serotonin) receptor 1E G protein coupled antibody
    • 5 hydroxytryptamine 1E receptor antibody
    • 5-HT-1E antibody
    • 5-hydroxytryptamine receptor 1E antibody
    • 5HT1E Receptor antibody
    • HTR1E antibody
    • S31 antibody
    • Serotonin receptor 1E antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human skin tissue labelling S31 with ab140506 at 10 µg/ml.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labelling S31 with ab140506 at 10 µg/ml.

References

ab140506 has not yet been referenced specifically in any publications.

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