Product nameAnti-SAF-B2 antibody [6F7]
See all SAF-B2 primary antibodies
DescriptionMouse monoclonal [6F7] to SAF-B2
Tested applicationsSuitable for: WB, IP, IHC-P, ICC/IFmore details
Species reactivityReacts with: Mouse, Human
- Human brain cortex tissue.
Previously labelled as Scaffold attachment factor B2.
Storage instructionsShipped at 4°C. Upon delivery aliquot. Avoid freeze / thaw cycle.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein G purified
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
Our Abpromise guarantee covers the use of ab67344 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: Use at a concentration of 5 µg/ml.
IP: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 108 kDa.
N.B. on SDS PAGE gels, Scaffold attachment factor B2 runs as an approximately 130 kDa protein. This aberrant migration is due to a large number of charged amino acid residues.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionBinds to scaffold/matrix attachment region (S/MAR) DNA. Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
Tissue specificityExpressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
Sequence similaritiesContains 1 RRM (RNA recognition motif) domain.
Contains 1 SAP domain.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- DKFZP779C1727 antibody
- HAP antibody
- HET antibody
ab67344 has not yet been referenced specifically in any publications.