Overview

  • Product name

    Saikosaponin A, triterpenoid saponin
  • Description

    Saikosaponin D epimer
  • Biological description

    Saikosaponin D (ab143545) epimer. COX-2 and iNOS inhibitor. Inhibits NF-κB, TNF-α, IL-1β and IL-6. Shows anti-inflammatory and antiallergic effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    20736-09-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Zhu J  et al. Saikosaponin A mediates the inflammatory response by inhibiting the MAPK and NF-?B pathways in LPS-stimulated RAW 264.7 cells. Exp Ther Med 5:1345-1350 (2013). Read more (PubMed: 23737876) »
  • Lu CN  et al. Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-?B signaling pathway. Int Immunopharmacol 14:121-6 (2012). Read more (PubMed: 22728095) »
  • Park KH  et al. Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma. Phytother Res 16:359-63 (2002). Read more (PubMed: 12112293) »

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