Product nameSalinomycin sodium salt, cation ionophore
DescriptionCation ionophore. Antibiotic agent.
Cation ionophore. Antibiotic agent. Salinomycin (ab141186) salt. Shows cancer stems cell selective antiproliferative effects (IC50 values are 24 and 90 μM for cancer stem cell subpopulation and HMLER breast cancer cells respectively). Shows antitumor effects in vivo.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
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This product has been referenced in:
- Zhou S et al. Salinomycin: a novel anti-cancer agent with known anti-coccidial activities. Curr Med Chem 20:4095-101 (2013). Read more (PubMed: 23931281) »
- Matsumori N et al. Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles. J Am Chem Soc 129:14989-95 (2007). Read more (PubMed: 17994744) »
- Schäfer H et al. Cationophore properties of the new polyether antibiotic Salinomycin investigated in distal rabbit colon in vivo and in vitro. Comp Biochem Physiol A Comp Physiol 79:387-92 (1984). Read more (PubMed: 6149842) »