Salmeterol xinafoate, beta2 adrenoceptor agonist (ab120771)

Overview

  • Product name

    Salmeterol xinafoate, beta2 adrenoceptor agonist
  • Description

    Selective, long acting β2 adrenoceptor agonist
  • Biological description

    Selective, long acting β2 adrenoceptor agonist. Inhibits release of histamine, leukotrienes, prostaglandin D2 and GM-CSF in concentration-dependent manner. Active in vitro and in vivo.
  • Purity

    > 96%
  • CAS Number

    94749-08-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol xinafoate
  • Molecular weight

    603.75
  • Molecular formula

    C25H37NO4.C11H8O3
  • PubChem identifier

    56801
  • Storage instructions

    Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in ethanol to 25 mM and in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    OCc1cc(ccc1O)C(O)CNCCCCCCOCCCCc2ccccc2.O=C(O)c2ccc1ccccc1c2O
  • Source

    Synthetic

References

This product has been referenced in:

  • Fuso L  et al. Long-acting beta-agonists and their association with inhaled corticosteroids in COPD. Curr Med Chem 20:1477-95 (2013). Read more (PubMed: 23409722) »
  • Akabane H  et al. Effects of salmeterol xinafoate and fluticasone propionate on immunological activation of human cultured mast cells. Allergol Int 55:387-93 (2006). Read more (PubMed: 17130681) »
  • Brogden RN & Faulds D Salmeterol xinafoate: a review of its pharmacological properties and therapeutic potential in reversible obstructive airways disease. Allergol Immunopathol (Madr) 20:72-84 (0). Read more (PubMed: 1359777) »
See all 3 Publications for this product

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