Overview

  • Product name

    Salsolidine, MAOinhibitor
  • Description

    Steroselective competitive MAOA inhibitor
  • Biological description

    Steroselective competitive MAOA inhibitor (Ki = 6 μM). R-enantiomer of Salsolinol (ab120603). Competitive catechol-O-methyltransferase inhibitor (Ki = 440 μM). Active in vivo.
  • Purity

    > 98%
  • CAS Number

    493-48-1
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
  • Molecular weight

    207.27
  • Molecular formula

    C12H17NO2
  • PubChem identifier

    10302
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC1C2=CC(=C(C=C2CCN1)OC)OC
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Stammel W  et al. Demonstration of highly specific and sensitive antibodies to a naturally occurring tetrahydroisoquinoline alkaloid, salsolidine. Int J Biochem 25:917-27 (1993). Read more (PubMed: 8344447) »
  • Bembenek ME  et al. Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines. J Med Chem 33:147-52 (1990). Read more (PubMed: 2296014) »
  • Sanft K & Thomas H [Competitive inhibition of catechol-O-methyltransferase by the tetrahydroisoquinoline alkaloids salsolidine and 1-carboxysalsoline]. Z Naturforsch C 44:173-6 (0). Read more (PubMed: 2490067) »

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