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    salusin-alpha-antibody-ab232928.pdf

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Anti-Salusin alpha antibody (ab232928)

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Abpromise

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Salusin alpha antibody (ab232928)
  • Western blot - Anti-Salusin alpha antibody (ab232928)
  • Western blot - Anti-Salusin alpha antibody (ab232928)
  • Western blot - Anti-Salusin alpha antibody (ab232928)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Salusin alpha antibody (ab232928)
  • Western blot - Anti-Salusin alpha antibody (ab232928)
  • Western blot - Anti-Salusin alpha antibody (ab232928)

Key features and details

  • Rabbit polyclonal to Salusin alpha
  • Suitable for: IHC-P, WB
  • Reacts with: Mouse, Human
  • Isotype: IgG

You may also be interested in

Secondary
Product image
Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

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Overview

  • Product name

    Anti-Salusin alpha antibody
    See all Salusin alpha primary antibodies
  • Description

    Rabbit polyclonal to Salusin alpha
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Recombinant fragment (His-T7-tag) corresponding to Mouse Salusin alpha aa 125-313. Expressed in E.coli. N-terminal tags.
    Sequence:

    PIIHFPHPSRTEQYKKELKSWVQGNLTACGRSLFLFDEMDKLPPGLMEVL QPFLGPSWVVYGTNYRKAIFIFISNAGGEQINQVALEAWRSHRDREEISL QEVEPVISRAVMDNPQHGFWRSGIMEEHLLDAVVPFLPLQRHHVRHCVLN ELAQLGLEPSEEVVQAVLDSTTYFPEVEQLFSSNGCKTV


    Database link: Q8R1J9
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • IHC-P: Mouse cardiac muscle and skin tissues. WB: Mouse serum; Mouse liver and heart lysates; Recombinant mouse Salusin alpha protein.
  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab232928 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Cardiovascular
    • Blood
    • Other
    • Neuroscience
    • Neurotransmitter
    • Neuropeptides
    • More Neuropeptides
    • Neuroscience
    • Endocrine system
    • Hypothalamic pituitary adrenal axis

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)
  • Positive Controls

    • HeLa whole cell lysate (ab150035)
    • Mouse liver tissue lysate - total protein (ab29301)
    • HeLa whole cell lysate (ab29545)
    • Mouse heart normal tissue lysate - total protein (ab30291)

Applications

Our Abpromise guarantee covers the use of ab232928 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 20 µg/ml.
WB Use a concentration of 0.2 - 2 µg/ml. Predicted molecular weight: 36 kDa.

Target

  • Relevance

    Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.
  • Cellular localization

    Secreted
  • Database links

    • Entrez Gene: 27433 Human
    • Entrez Gene: 30933 Mouse
    • Entrez Gene: 362112 Rat
    • Omim: 608052 Human
    • SwissProt: Q5JU69 Human
    • SwissProt: Q8N2E6 Human
    • SwissProt: P0C7W3 Mouse
    • SwissProt: Q8R1J9 Mouse
    • SwissProt: P0C7W2 Rat
    • SwissProt: Q6AYR4 Rat
    • Unigene: 444106 Human
    • Unigene: 200695 Mouse
    • Unigene: 13187 Rat
    see all
  • Alternative names

    • prosalusin antibody
    • Prosalusin precursor antibody
    • TOR2A antibody
    • TORP1 antibody
    • Torsin 2A [Precursor] antibody
    • torsin 2A antibody
    • Torsin family 2 member A antibody
    • Torsin related protein 1 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Salusin alpha antibody (ab232928)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Salusin alpha antibody (ab232928)

    Paraffin-embedded mouse cardiac muscle tissue stained for Salusin alpha using ab232928 at 10 µg/ml in immunohistochemical analysis. DAB staining.

  • Western blot - Anti-Salusin alpha antibody (ab232928)
    Western blot - Anti-Salusin alpha antibody (ab232928)
    Anti-Salusin alpha antibody (ab232928) at 1 µg/ml + Mouse liver lysate

    Secondary
    HRP-Linked Goat anti-Rabbit IgG polyclonal at 0.2 µg/ml

    Predicted band size: 36 kDa

  • Western blot - Anti-Salusin alpha antibody (ab232928)
    Western blot - Anti-Salusin alpha antibody (ab232928)
    Anti-Salusin alpha antibody (ab232928) at 1 µg/ml + Mouse heart lysate

    Secondary
    HRP-Linked Goat anti-Rabbit IgG polyclonal at 0.2 µg/ml

    Predicted band size: 36 kDa

  • Western blot - Anti-Salusin alpha antibody (ab232928)
    Western blot - Anti-Salusin alpha antibody (ab232928)
    Anti-Salusin alpha antibody (ab232928) at 1 µg/ml + HeLa (human epithelial cell line from cervix adenocarcinoma) cell lysate

    Secondary
    HRP-Linked Goat anti-Rabbit IgG polyclonal at 0.2 µg/ml

    Predicted band size: 36 kDa

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Salusin alpha antibody (ab232928)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Salusin alpha antibody (ab232928)

    Formalin-fixed, paraffin-embedded mouse skin tissue stained for Salusin alpha using ab232928 at 10 µg/ml in immunohistochemical analysis. DAB staining.

  • Western blot - Anti-Salusin alpha antibody (ab232928)
    Western blot - Anti-Salusin alpha antibody (ab232928)
    Anti-Salusin alpha antibody (ab232928) at 1 µg/ml + Mouse serum

    Secondary
    HRP-Linked Goat anti-Rabbit IgG polyclonal at 0.2 µg/ml

    Predicted band size: 36 kDa

  • Western blot - Anti-Salusin alpha antibody (ab232928)
    Western blot - Anti-Salusin alpha antibody (ab232928)
    Anti-Salusin alpha antibody (ab232928) at 2 µg/ml + Recombinant mouse Salusin alpha protein

    Predicted band size: 36 kDa

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab232928? Please let us know so that we can cite the reference in this datasheet.

    ab232928 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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