Key features and details
- Potent κ agonist
- CAS Number: 83729-01-5
- Soluble in ethanol to 10 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Salvia Divinorum
Product nameSalvinorin A (Divinorin A), kappa agonist
DescriptionPotent κ agonist
- Divinorin A
Potent κ agonist (Ki = 8-19 nM). Psychoactive and antinociceptive in vivo. Reported to be an allosteric modulator of μ opioid receptors.
Chemical name(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)dodechydro-6a,10b-dimethyl-4,10-dioxo-2H-naptho[2,1-c]pyran-7-carboxylic acid methyl ester
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 10 mM and in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120084 has been referenced in 1 publication.
- Pittaluga A et al. Effects of the neoclerodane Hardwickiic acid on the presynaptic opioid receptors which modulate noradrenaline and dopamine release in mouse central nervous system. Neurochem Int 62:354-9 (2013). PubMed: 23357481