Overview

  • Product name

  • Description

    Rabbit polyclonal to SAMSN1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    An 18 amino acid synthetic peptide near the C terminus of Human SAMSN1.

  • Positive control

    • HeLa cell lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab139735 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 42 kDa.

Target

  • Function

    Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.
  • Tissue specificity

    Detected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
  • Sequence similarities

    Contains 1 SAM (sterile alpha motif) domain.
    Contains 1 SH3 domain.
  • Cellular localization

    Nucleus. Cytoplasm. Cell projection > ruffle. Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles.
  • Information by UniProt
  • Database links

  • Alternative names

    • HACS1 antibody
    • Hematopoietic adapter containing SH3 and sterile α motif (SAM) domains 1 antibody
    • Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1 antibody
    • Hematopoietic adaptor containing SH3 and SAM domains 1 antibody
    • Nash1 antibody
    • Nuclear localization signals SAM and SH3 domain containing 1 antibody
    • SAM and SH3 domain containing 2 antibody
    • SAM domain antibody
    • SAM domain containing protein SAMSN 1 antibody
    • SAM domain SH3 domain and nuclear localisation signals 1 antibody
    • SAM domain SH3 domain and nuclear localization signals 1 antibody
    • SAM domain, SH3 domain and nuclear localization signals protein 1 antibody
    • SAM domain-containing protein SAMSN-1 antibody
    • SAMN1_HUMAN antibody
    • SAMSN 1 antibody
    • Samsn1 antibody
    • SASH2 antibody
    • SH3 domain and nuclear localisation signals 1 antibody
    • SH3 domain and nuclear localization signals protein 1 antibody
    • SH3 SAM adaptor protein antibody
    • SH3-SAM adaptor protein antibody
    • SH3D6B antibody
    • SLy2 antibody
    • Src homology domain 3 (SH3) containing adapter protein SH3 lymphocyte protein 2 antibody
    see all

Images

  • Lane 1 : Anti-SAMSN1 antibody (ab139735) at 0.5 µg/ml
    Lane 2 : Anti-SAMSN1 antibody (ab139735) at 1 µg/ml

    All lanes : HeLa cell lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 42 kDa

References

ab139735 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab139735.
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