Product nameAnti-SAMSN1 antibody
See all SAMSN1 primary antibodies
DescriptionGoat polyclonal to SAMSN1
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Human
IRLDTLSASLGRS-C(Human) Please note that the immunogen sequence is present in NP_071419.2 (and in AAK07746) but is no longer present in the latest reference sequence (NP_071419.3 at 05/10/05). This latest version has not been subject to final review by NCBI. This antibody may be recognising one particular isoform.
- Jurkat lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline. pH 7.3
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab21206 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 48 kDa in Jurkat cell lysates (predicted molecular weight: 42 kDa). The observed size is consistent with observations with competing products.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionNegative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation.
Tissue specificityDetected in peripheral blood B-cells (at protein level). Detected in spleen, liver and peripheral blood.
Sequence similaritiesContains 1 SAM (sterile alpha motif) domain.
Contains 1 SH3 domain.
Cellular localizationNucleus. Cytoplasm. Cell projection > ruffle. Shuttles between cytoplasm and nucleus. Colocalizes with the actin cytoskeleton and actin-rich membrane ruffles.
- Information by UniProt
- HACS1 antibody
- Hematopoietic adapter containing SH3 and sterile α motif (SAM) domains 1 antibody
- Hematopoietic adapter containing SH3 and sterile alpha motif (SAM) domains 1 antibody
ab21206 has not yet been referenced specifically in any publications.