Overview

  • Product name

  • Description

    Rabbit polyclonal to SAP18
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Zebrafish, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human SAP18 (internal sequence). The exact sequence is proprietary.
    Database link: O00422

  • Positive control

    • WB: K562 whole cell and nuclear extracts.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.025% Proclin
    Constituents: PBS, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab226757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 18 kDa.

Target

  • Function

    Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.
  • Tissue specificity

    Ubiquitous.
  • Sequence similarities

    Belongs to the SAP18 family.
  • Cellular localization

    Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • 18 kDa Sin3-associated polypeptide antibody
    • 2HOR0202 antibody
    • Cell growth-inhibiting gene 38 protein antibody
    • Histone deacetylase complex subunit SAP18 antibody
    • SAP18 antibody
    • SAP18_HUMAN antibody
    • Sin3-associated polypeptide p18 antibody
    see all

Images

  • All lanes : Anti-SAP18 antibody (ab226757) at 1/1000 dilution

    Lane 1 : K562 (human chronic myelogenous leukemia cell line from bone marrow ) whole cell extract
    Lane 2 : K562 (human chronic myelogenous leukemia cell line from bone marrow ) nuclear extract

    Lysates/proteins at 30 µg per lane.

    Developed using the ECL technique.

    Predicted band size: 18 kDa

References

ab226757 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab226757.
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