Sarafloxacin hydrochloride, Fluoroquinolone antibiotic agent (ab143452)

Overview

  • Product name

    Sarafloxacin hydrochloride, Fluoroquinolone antibiotic agent
  • Description

    Fluoroquinolone broad spectrum antibiotic
  • Biological description

    Fluoroquinolone broad spectrum antibiotic. Inhibits the topoisomerase II ligase domain. Shows activity against Mycobacterium tuberculosis in vivo. Orally active.
  • Purity

    > 91%
  • CAS Number

    91296-87-6
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid hydrochloride
  • Molecular weight

    421.83
  • Molecular formula

    C20H18ClF2N3O3
  • PubChem identifier

    56207
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=CC=C(C=C4)F)F.Cl
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Tao X  et al. Chemiluminescence competitive indirect enzyme immunoassay for 20 fluoroquinolone residues in fish and shrimp based on a single-chain variable fragment. Anal Bioanal Chem 405:7477-84 (2013). Read more (PubMed: 23842902) »
  • Fernandez-Teruel C  et al. Kinetic modelling of the intestinal transport of sarafloxacin. Studies in situ in rat and in vitro in Caco-2 cells. J Drug Target 13:199-212 (2005). Read more (PubMed: 16036308) »
  • McConville ML  et al. Effects of sarafloxacin hydrochloride on human enteric bacteria under simulated human gut conditions. Vet Q 17:1-5 (1995). Read more (PubMed: 7610549) »

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