Key features and details
- Potent, highly selective ETB endothelin receptor agonist
- CAS Number: 121695-87-2
- Purity: > 97%
- Form / State: Lyophilized
- Source: Synthetic
Product nameSarafotoxin S6c, ETB endothelin receptor agonist
DescriptionPotent, highly selective ETB endothelin receptor agonist
Potent, highly selective ETB endothelin receptor agonist (Ki values are 0.29 and >1000 nM for ETB and ETA respectively). Activates PI turnover in the hippocampus (EC50 = 10 nM). Shows potent pressor effects and induces smooth muscle contraction in vivo.
Chemical nameCTCNDMTDEECLNFCHQDVIW (Modification: Disulfide bridges: 1-15 and 3-11)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141006 has not yet been referenced specifically in any publications.