Product nameAnti-SARS Nucleocapsid Protein antibody
DescriptionMouse polyclonal to SARS Nucleocapsid Protein
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivitySARS virus.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituent: Whole serum
Our Abpromise guarantee covers the use of ab26854 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Predicted molecular weight: 46 kDa.|
RelevanceSevere Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has recently been attributed to a novel coronavirus (SARS-CoV). SARS is caused by a human coronavirus, which are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. The nucleocapsid protein of SARS shares little homology with nucleocapsid proteins of other members of the coronavirus family. Nucleocapsid proteins of other coronavirus have been reported to be involved in forming the viral core and also in the packaging and transcription of the viral RNA.
Cellular localizationInside the virion, complexed with the viral RNA. May be associated with cellular membranes where it participates in viral RNA synthesis and virus budding.
- N antibody
- NC antibody
- Nucleocapsid protein antibody
Anti-SARS Nucleocapsid Protein antibody (ab26854) at 1/500 dilution + 400ng of recombinant SARS CoV Nucleocapsid protein
HRP conjugated anti mouse IgG
Predicted band size: 46 kDa
Observed band size: 60 kDa why is the actual band size different from the predicted?
ab26854 has not yet been referenced specifically in any publications.