Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [CR3018 (03-018)] to SARS Nucleocapsid Protein
- Suitable for: ELISA
Product nameAnti-SARS Nucleocapsid Protein antibody [CR3018 (03-018)]
See all SARS Nucleocapsid Protein primary antibodies
DescriptionRabbit monoclonal [CR3018 (03-018)] to SARS Nucleocapsid Protein
Tested applicationsSuitable for: ELISAmore details
Species reactivityReacts with: SARS-CoV, SARS-CoV-2
Tissue, cells or virus corresponding to Human SARS Nucleocapsid Protein. This antibody binds the amino acid residues between 11-19 of the N protein of the SARS CoV as well as SARS-CoV-2 (COVID-19) Nucleocapsid Protein.
Database link: P0DTC9, P59595
- ELISA: SARS-CoV-2 Nucleocapsid Proteins.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Proclin 300
Constituent: 99.98% PBS
Concentration information loading...
PurityProtein A purified
Clone numberCR3018 (03-018)
Light chain typekappa
Our Abpromise guarantee covers the use of ab275983 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use a concentration of 10 µg/ml.
A 3-fold serial dilution from 10,000 ng/ml.
RelevanceSevere Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has recently been attributed to a novel coronavirus (SARS-CoV). SARS is caused by a human coronavirus, which are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. The nucleocapsid protein of SARS shares little homology with nucleocapsid proteins of other members of the coronavirus family. Nucleocapsid proteins of other coronavirus have been reported to be involved in forming the viral core and also in the packaging and transcription of the viral RNA.
Cellular localizationInside the virion, complexed with the viral RNA. May be associated with cellular membranes where it participates in viral RNA synthesis and virus budding.
- N antibody
- NC antibody
- Nucleocapsid protein antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab275983 has not yet been referenced specifically in any publications.